httkexamples - High-Throughput Toxicokinetics Examples
High throughput toxicokinetics ("HTTK") is the combination
of 1) chemical-specific in vitro measurements or in silico
predictions and 2) generic mathematical models, to predict
absorption, distribution, metabolism, and excretion by the
body. HTTK methods have been described by Pearce et al. (2017)
(<doi:10.18637/jss.v079.i04>) and Breen et al. (2021)
(<doi:10.1080/17425255.2021.1935867>). Here we provide examples
(vignettes) applying HTTK to solve various problems in
bioinformatics, toxicology, and exposure science. In accordance
with Davidson-Fritz et al. (2025)
(<doi:10.1371/journal.pone.0321321>), whenever a new HTTK model
is developed, the code to generate the figures evaluating that
model is added as a new vignettte.
