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# CITATION file created with {cffr} R package
# See also: https://docs.ropensci.org/cffr/
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cff-version: 1.2.0
message: 'To cite package "httkexamples" in publications use:'
type: software
license: MIT
title: 'httkexamples: High-Throughput Toxicokinetics Examples'
version: 0.0.1
doi: 10.18637/jss.v079.i04
identifiers:
- type: doi
  value: 10.32614/CRAN.package.httkexamples
abstract: High throughput toxicokinetics ("HTTK") is the combination of 1) chemical-specific
  in vitro measurements or in silico predictions and 2) generic mathematical models,
  to predict absorption, distribution, metabolism, and excretion by the body. HTTK
  methods have been described by Pearce et al. (2017) (<https://doi.org/10.18637/jss.v079.i04>)
  and Breen et al. (2021) (<https://doi.org/10.1080/17425255.2021.1935867>). Here
  we provide examples (vignettes) applying HTTK to solve various problems in bioinformatics,
  toxicology, and exposure science. In accordance with Davidson-Fritz et al. (2025)
  (<https://doi.org/10.1371/journal.pone.0321321>), whenever a new HTTK model is developed,
  the code to generate the figures evaluating that model is added as a new vignettte.
authors:
- family-names: Wambaugh
  given-names: John
  email: john.wambaugh@UL.org
  orcid: https://orcid.org/0000-0002-4024-534X
- family-names: Pearce
  given-names: Robert
  orcid: https://orcid.org/0000-0003-3168-4049
- family-names: Ring
  given-names: Caroline
  email: Ring.Caroline@epa.gov
  orcid: https://orcid.org/0000-0002-0463-1251
- family-names: Honda
  given-names: Greg
  email: honda.gregory@epa.gov
  orcid: https://orcid.org/0000-0001-7713-9850
- family-names: Linakis
  given-names: Matt
  email: MLINAKIS@ramboll.com
  orcid: https://orcid.org/0000-0003-0526-2395
- family-names: Kapraun
  given-names: Dustin
  email: kapraun.dustin@epa.gov
  orcid: https://orcid.org/0000-0001-5570-6383
- family-names: Truong
  given-names: Kimberly
  email: truong.kimberly@epa.gov
  orcid: https://orcid.org/0000-0003-1716-1006
- family-names: Scherer
  given-names: Meredith
  email: Scherer.Meredith@epa.gov
  orcid: https://orcid.org/0000-0002-9785-7363
- family-names: Meade
  given-names: Annabel
  email: aemeade7@gmail.com
  orcid: https://orcid.org/0000-0002-5452-8797
- family-names: Schacht
  given-names: Celia
  email: Schacht.Celia@epa.gov
  orcid: https://orcid.org/0000-0002-8131-513X
preferred-citation:
  type: article
  title: 'httk: R Package for High-Throughput Toxicokinetics'
  authors:
  - family-names: Pearce
    given-names: Robert G.
  - family-names: Setzer
    given-names: R. Woodrow
  - family-names: Strope
    given-names: Cory L.
  - family-names: Sipes
    given-names: Nisha S.
  - family-names: Wambaugh
    given-names: John F.
    email: wambaugh.research@gmail.com
  journal: Journal of Statistical Software
  year: '2017'
  volume: '79'
  issue: '4'
  doi: 10.18637/jss.v079.i04
  start: '1'
  end: '25'
repository: https://wambaughul.r-universe.dev
commit: f98d97a130b1c257e689749454589ee7fea43860
url: https://chemicalinsights.ul.org/
date-released: '2025-12-03'
contact:
- family-names: Wambaugh
  given-names: John
  email: john.wambaugh@UL.org
  orcid: https://orcid.org/0000-0002-4024-534X